The sudden death of former One Direction member Liam Payne shocked the entertainment world, leaving fellow stars devastated, including an artist he once collaborated with on a major project.
Tributes from fellow stars continue to pour in as the entertainment world mourns the loss of Liam Payne, who tragically died at 31 after falling from a hotel balcony in Buenos Aires, Argentina, on October 16.
Music producer Zedd was heartbroken and shared his grief on X (formerly Twitter) even though he couldn’t believe the news.
TV personality and DJ Paris Hilton also expressed sadness as she ended her tweet with “RIP my friend🥺.”
More musicians honored Payne with heartfelt condolences. Rapper Flavor Flav kept his message short but heartfelt acknowledging that the musician was too young to die.
British DJ and songwriter Jonas Blue also said farewell on the same platform as he posted a picture of himself and Payne.
Anne Twist, Harry Styles’ mother, reacted to Payne’s death with a heartbroken emoji on a black background on Instagram. In her caption, she wrote, “Just a boy … 💔.”
Singer-songwriter Charlie Puth shared his heartbreak on his Instagram (IG) Story as he reminisced about the kind of person Payne was to him.
In another IG Story, an upset Puth shared an old photo of him and Payne smiling at each other.
Just weeks before his passing, the late English musician supported Niall Horan by attending the Irish singer and songwriter’s concert on October 3.
Payne was excited to go to the concert and shared a Snapchat photo of Horan performing, captured from the large screen.
In another picture he shared, he captured the audience with their phones held up and the purple-lit stage as he was proud of his friend.
He also shared a backstage photo with Horan, where Payne wore a dark-colored jacket over a light-colored t-shirt while his famous pal sported a striped shirt. Both looked in good spirits.
Before attending Horan’s concert, Payne had celebrated his 31st birthday on August 29. He wrote about his simple wish for the day in a post as he walked alone on the street in a gray hoodie.
While tributes continue to pour in, authorities are still investigating the circumstances of Payne’s tragic death. According to TMZ, Payne fell from the third-floor balcony of the CasaSur Palermo Hotel.
Earlier that day, hotel staff called emergency services after he was reportedly acting erratically in the lobby, smashing a laptop and needing to be carried back to his room.
Alberto Crescenti, the director of Buenos Aires Emergency Medical Services, told ABC News that emergency services arrived at 5:11 p.m., just a few minutes after the hotel’s call. Unfortunately, there was no possibility of saving Payne, whose identity was only confirmed after he was pronounced dead.
Crescenti added that Payne’s body was found in the hotel’s inner courtyard. He further explained to the local media outlet TN that the singer fell from a height of 13 to 14 meters (42 to 45 feet) and described his injuries as “very serious” and “incompatible with life.”
Before the incident, Payne traveled to Argentina with his girlfriend, Kate Cassidy, for a vacation besides attending Horan’s concert. However, his girlfriend reportedly left on October 14, while Payne remained behind.
With his recent death, Payne is survived by his son, Bear, whom he shares with singer Cheryl Cole. The couple confirmed they were expecting their first child in November 2016, with Bear born in 2017.
In a 2018 interview, Payne discussed the joys and challenges of fatherhood. He said, “I always wanted to be a young dad, but I didn’t really expect that I’d ever be in this place.”
Payne also humorously referred to himself as “Dada Montana” as he balanced his music career with being a parent. Before becoming a dad, he gained fame at 16 when he joined the One Direction boy band.
The group was launched on “The X Factor,” alongside Niall Horan, Harry Styles, Louis Tomlinson, and Zayn Malik. Payne played a key role in their global success until the band disbanded in 2015.
The entertainment industry continues to mourn the loss of a beloved artist, with fellow stars remembering his talent and kindness. Our prayers go out to his family and all the fans who loved him.
We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
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