Tragic News Regarding Frank Fritz of the American Pickers

There are many surprises in life, some happy and others sad. Many people know Frank Fritz as their favorite television personality. He has seen highs and lows in his career. His tale is, in fact, heartwarming.

Frank and Diann Bankson were longtime partners. Regrettably, their breakup had a very negative impact on him, resulting in problems with alcohol, unemployment, and health issues.

Frank and Diann dated intermittently for years, starting when they were 25 years old. After becoming engaged in 2017, they planned a lovely life together and purchased a charming farmhouse in Iowa. However, in the latter part of 2018, things became worse.

Their romance was destroyed when Diann caught Frank with another woman. Frank eventually opened up about how much the betrayal upset him and how it motivated him to get a tattoo as a painful memento.

Frank said, “I bought a house, an expensive ring, and I was going to marry her.” Finding out about her adultery was too much to take. Frank turned to drink as a coping mechanism for the pain and lost a lot of weight at this time.

Frank made the decision to stop dating and concentrate on beating his drinking issue after they broke up.

Frank too had turmoil in his career. His time on the History Channel series “American Pickers” ended in March 2020, allegedly because of health issues following back surgery.

Frank expressed his enthusiasm to rejoin the show once he healed and wanted to return after recovering. But there were no firm arrangements for his return, and it appeared that the performance was going forward without him.

Diann continued living her life, posting pleasant moments on social media with her new lover, Eric Longlett, while Frank struggled with these setbacks.

Frank was admitted to the hospital after suffering a stroke on July 4, 2022. Upon discovering him on the ground, his companion promptly dialed for assistance.

Although Frank’s son was improving, his recuperation was taking a while. Frank was released from the hospital, put under guardianship, and admitted to a care home.

In order to oversee his financial and personal matters and guarantee he received the attention and assistance he required, a close friend was named as his temporary conservator and guardian.

Medical reports state that Frank’s health necessitated ongoing supervision and help with everyday tasks, doctor appointments, and general well-being.

The court acknowledged that Frank needed a guardian to watch out for his health and safety and emphasized that without that kind of support, Frank stood the risk of his illness getting worse.

It is so sad to hear about Frank Fritz. We’re sending him our best wishes and thoughts for a quick recovery. Giving your loved ones access to this information can help them stay up to date on the happenings with their favorite TV host.

We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth

The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.

A dental breakthrough

While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.

A bit of science

The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.

As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.

On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.

BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.

“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.

The first results

Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.

“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.

Fully regrown frontal teeth in ferrets

The next steps

Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontiaa genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.

Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.

“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”

So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.

Preview photo credit KyotoU_News / Twitter

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